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Description
From a regulatory standpoint, tesamorelin is clear-cut: it is fully FDA-approved for reducing excess abdominal fat in individuals with HIV-associated lipodystrophy (FDA, 2025)

It binds to GHRH receptors in the anterior pituitary to initiate the production and release of growth hormone

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This represents the most common starting point in practical protocols and aligns with the midpoint of clinical dosing ranges adjusted for average body composition
