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20 Systematic reviews: Oral vitamin B 12 replacement for the treatment of pernicious anemia 21 Relevant articles were identified by PubMed search from January 1, 1980 to March 31, 2016, focusing on patients with pernicious anemia

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The initial shots were used to rapidly refill them, prevent further nerve damage, and help heal recent damage

This effect is believed to be due to IGF-1 suppression of insulin secretion, which leads to augmented lipolysis in adipose tissue and promotion of FFA use by muscle
