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For instance, the antitumor agent PABA/NO (O 2 [2,4dinitro-5(Nmethyl-N4carboxyphenylamino)phenyl]1-(N,Ndimethylamino)diazen-1ium1, 2diolate) triggered a dose-dependent increase in the intracellular NO levels in SKOV3 adenocarcinoma and HL60 promyelocytic leukemia cells followed by the development of nitrosative stress along with activation of Sglutathionylation of proteins, including lactate dehydrogenase, Rho GDP dissociation inhibitor beta, ATP synthase, elongation factor 2, PDI, nucleophosmin 1, chaperonin, actin, protein tyrosine phosphatase 1B, and glucosidase II [70]

GSH joins with heavy metals to neutralize them and eliminate them from the body

(Hunter et al., 2020)

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