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Glycerol phenylbutyrate (GPB) is a medication approved by the Food and Drug Administration in 2013 for the treatment of patients with urea cycle disorders or innate metabolism errors that manifest as hyperammonemia, whose effect was emulated in the cirrhotic population.49 GPB is hydrolyzed by pancreatic lipases for producing glycerol and 3 molecules of phenylbutyric acid

[DOI] [PubMed] [Google Scholar] 115.Tavafoghi M., Cerruti M

Although the authors generated multiple tissue-specific Slc25a45 KO models and concluded that systemic carnitine availability reflects coordinated contributions from multiple organs, fuel reliance is likely to vary with dietary regimen, metabolic state, and pathology

Acute Exacerbation of Chronic Cholecystitis Revealing a Duplicate Gallbladder: A Rare Surgical Challenge