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However, when GPX4 is inactivated or when GSH is depleted in cells, phospholipid peroxides (PLOOH) accumulate, leading to the generation of lipid radicals, such as lipid peroxyl radicals ((P)LOO) and alkyl radicals ((P)L), through iron-dependent free radical chain reactions 10,16,17

Protective effect of Procyanidin B 2 on hydrogen peroxide (H 2 O 2 )-induced oxidative damage in MCF-7 cells

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required for myelin synthesis) causing human diseases 9,10
