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Notably, EC, which contains fewer phenolic groups, exhibits higher bioavailability than the more structurally complex EGCG (Ouyang et al

In older people, absorption can be insufficient because the amount of stomach acid decreases in old age [1]

Such trials should ideally investigate the impact of methotrexate alone, folic acid alone and methotrexate in combination with folic acid and include a non-methotrexate/folic acid comparator arm to fully determine the atheroprotective potential of methotrexate

Using these two models we search for genes involved in vascular morphogenesis and ask funtional/mechanistic questions using genetics (transgenics and knock-outs in the case of the mouse) and molecular biology (transfection or chicken embryos using electroporation)