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Several independent studies have also shown that treatment with arimoclomol, a co-inducer of heat shock proteins, is protective against toxic mutant SOD1 aggregates, delays disease progression and improves motor function in SOD1 G93A mice (Kieran et al., 2004

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The interest of researchers should be directed into the development of new serological parameters useful in the monitoring of the disease, as well as verifying the efficacy of ongoing treatment