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Description
The mechanisms involve IGF-1-driven activation of the PI3K-Akt pathway in fibroblasts and epithelial cells, promoting both proliferation and survival during the repair process
Sigma-Aldrich) at various concentrations or with 0.1% ethanol (vehicle control) at the beginning of day 1 of culture

Let the inflammation settle and the skin barrier stabilise

Thus, in some embodiments, an otic composition or formulation disclosed herein is free or substantially free of alcohols, propylene glycol, and cyclohexane
