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The safety profile of semaglutide 2.4 mg in STEP 5 was consistent with that in other STEP program trials 6,7,9,16,23 , and with the GLP-1 receptor agonist class in general 28
This refined understanding of CNS scarring underscores the dynamic roles of both astrocytes and fibroblasts, shifting the paradigm from a simplistic view of the glial scar to a more nuanced appreciation of the interplay between glial and fibrotic components
Alternative volumes for different resulting concentrations Rule: For Cagrilintide we recommend 2 ml as the optimal compromise volume
Figure 6: Drug-Induced Liver Injury
