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In the UK, hydroxocobalamin is the preferred formulation, typically maintaining therapeutic levels for 8 to 12 weeks

The NLRP3 inflammasome in ECs can be caused by stimuli such as low-density lipoprotein oxidized, hyperglycemia, and nicotine, thus leading to the death of ECs [84, 85]

2019;14(2) doi: 10.1371/journal.pone.0211942

Germline variants associated with toxicity to immune checkpoint blockade
