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Description
Mutations in the HSD11B2 gene are associated with an apparent mineralocorticoid excess-induced hypertension due to the lack of ability to inactivate cortisol
Specifically, the pump transports three sodium ions out of the cell and two potassium ions into the cell during each cycle
The strongest mitochondrial FAO activity has been observed in the proximal and distal convoluted tubules (Wirthensohn and Guder, 1986)
Schrader, Meier, & Brattstrm, 1998
