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Tirzepatide was administered at a dose assumed to be below the lowest clinically applicable dose of 5 mg, based on C max [46], and the same dose was used for retatrutide
Intriguingly, the authors showed undetectable promoter activity upstream miR-483, which is located within intron 7 of the IGF2 gene
For a 12-week protocol , estimated use increases to approximately 58.8 mg , requiring 6 vials
