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the adoptive transfer of M2 instead of M1 macrophages had a considerable impact of decreasing the intensity of SLE in clodronate-treated mice and Activated Lymphocyte-Derived DNA (ALD-DNA) (100)
Therefore, human plasma TdR level does not appear to be a useful PD phenotypic marker for TS inhibition

I, unfortunately, I was just the supplier and I was just the maker of the product, but we saved so many lives

Kraml M
