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Myelin dysfunction resulting from chronic hypoxia has been shown to cause profound synaptic deficits, while enhanced myelin renewal effectively reversed these deficits [21]

Reduced CB1 receptor expression has been observed in postmortem brain samples from human cocaine addicts (lvaro-Bartolom and Garca-Sevilla, 2013), and this was recapitulated in mice exposed to cocaine

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Tahaghoghi-Hajghorbani S, Zafari P, Masoumi E, Rajabinejad M, Jafari-Shakib R, Hasani B, et al
