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doi:10.1073/pnas.2010217118

Therefore, it is recommended to investigate gene expression and protein levels involved in the biogenesis up-and-down-regulation of the signaling pathway

The response to cerebral ischemia was proportional to the blood perfusion rate: the most pronounced in the hippocampus, followed by the cortex and the lowest extent of metabolic changes were observed in the cerebellum

World Health Organization, 2018)
