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Currently, several important guidelines, including International Atherosclerosis Society (IAS) guideline [20], National Lipid Association (NLA) guideline and National Institute for Health and Care Excellence (NICE) guideline [21], have flagged non-HDL-C as a primary therapeutic target for patients with CHD

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Interestingly, this interaction is usually bidirectional, whereby immune cells also influence fibroblast behaviour ( in vitro cultures, Zhou et al
