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After getting a B12 shot, you should watch out for these symptoms and see a doctor if you have: Strong pain where you got the shot Some stomach upset Feeling swollen Skin feeling itchy for a while In really rare cases, there might be more serious risks like: A severe allergic reaction called anaphylaxis Fluid build-up in the lungs Heart problems Blood clots in the bodys blood vessels A type of blood cancer, called polycythemia vera

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So, when possible, I like to add cocoa butter, since it melts at around 93-100 degrees, making it easier to keep the suppository intact until it gets where its supposed to go

Discuss your specific medical history with a prescribing provider