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The FDAs own language makes it clear: Compounded drugs containing BPC-157 may pose risk for immunogenicity and may have complexities with regard to peptide-related impurities and API characterization. In plain terms, the FDA is worried about shady, unregulated research-use-only peptides sold online not about what happens when BPC-157 is responsibly compounded, tested for purity, and dispensed under medical supervision

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Experts cautioned that more research is needed before broad conclusions can be drawn, but the results do provide some evidence that robust immunity is generated after one dose and that the second dose could be delayed beyond the three weeks prescribed by Pfizer in order to ease distribution and supply constraints