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Description
These channels define the pore pathway 47 (Box 1) and are exemplified by claudin-2, which mediates paracellular flux of small cations, such as Na + , and water 42,43,48,49
Overall, 5-Amino-1MQ represents a novel class of NNMT inhibitors with the potential to impact multiple physiological pathways
They are not magic bullets, so they work best layered onto a foundation of good training, protein, and sleep
A reader who believes evidence is being hidden looks for the smoking gun
