mitochondrial glutathione reductase Unearthing the secrets of ROS and in bioenergetics: Trends in Biochemical Sciences Mitochondrial Glutathione in Cellular Redox
Description
(2011) The antioxidant ascorbic acid mobilizes nuclear copper leading to a prooxidant breakage of cellular DNA: implications for chemotherapeutic action against cancer
Keywords: MTHFR, gene polymorphisms, C677T, A1298C, vitamin B, cardiovascular diseases, retinopathy, inflammation, folate 1
Small-molecule inhibitors of the GSH pathway, such as buthionine sulfoximine (BSO), block -glutamylcysteine ligase and GSH biosynthesis, thereby exacerbating the oxidative stress elicited by radiotherapy and cisplatin [214,215,216]
Schoffski P, Wozniak A, Escudier B, Rutkowski P, Anthoney A, Bauer S, et al
