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Additionally, T cell metabolism has emerged as a promising target to functionally restore antigen-specific T cells in the fields of oncology and chronic viral infections (17, 18)

The innovation of this research lies in: Unlike existing reviews, which often focus on either acute or chronic stages in isolation, this review adopts a full-cycle perspectivespanning acute lung injury to long-term sequelaeand incorporates biomarker-informed stratification to tailor exercise interventions

Hcar2 is widely expressed throughout the body, which likely explains the broad range of physiological and pharmacological effects that Hcar2 ligands such as niacin can have