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Syncope Sudden death (rare) Physical exam Mid-to-late systolic click (snapping of the mitral chordae during systole Systole Period of contraction of the heart, especially of the heart ventricles
From a public-health perspective, high-fiber dietary patterns enrich microbiota that generate less TMA, whereas low-fiber, high-meat diets tend to increase TMAO production
The large heterogeneity for some outcomes, such as CAD, may suggest different mechanisms underlying the genetic associations or the existence of pleiotropy [37]
Kienesberger K, Pordes AG, Vlk TG, Hofbauer R
