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The most important mechanism involved in acute OIPN is the alteration of voltage-gated Na + channels, and nuclear DNA damage in chronic OIPN

Superoxide Dismutase (SOD2) is a ubiquitous antioxidant that decreases with age, leaving the body open to ROS damage

Perspectives on the importance of delivery and the potential for an early combination approach

The Fascinating Interplay between Growth Hormone, Insulin-Like Growth Factor-1, and Insulin
