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Preparation of skin tissue homogenate The skin tissue was washed with normal saline and then minced using a pestle and mortar

Results We found that ALCAR reduces cell proliferation, induces apoptosis, hinders the production of pro inflammatory cytokines (TNF- and IFN-) and of chemokines CCL2, CXCL12 and receptor CXCR4 involved in the chemotactic axis and impairs the adhesion, migration and invasion capabilities of PCa and BPH cells in vitro

Thereafter, the cytosolic enzyme, CDO, catalyses the conversion of Cys to cysteine sulfinic acid, the initial step in the transsulfuration pathway that leads to the formation of inorganic sulfate and taurine [124] (Figure 2)