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Exons 1, 2 and 3 encode the protein p16, which binds to cyclin-dependent kinase 4 (CDK4), preventing interaction with cyclin D and inhibiting phosphorylation of the retinoblastoma protein (Rb) and thus passage from the G1 to S phases of the cell cycle

doi: 10.18632/oncotarget.6817 39 NakamuraMTNaraTY

Glucose concentrations 75 mg/dL were 100% accurate within 15%-20%, 98% accurate within 10%, and 75% accurate within 5% in 133 patients