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Each lactic acid microorganism contributes distinct role in fermentation
Recent studies further connect sustained Ca 2+ entry (via NMDAR or P2X7) to loss of mitochondrial membrane potential, increased mitochondrial ROS, and suppression of mitophagic clearance, collectively potentiating NLRP3 activation in microglia under HIV-related conditions [100]
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By administering the ferroptosis inducers RSL3 and IKE and knocking out the GPX4 gene in immortalized mouse fibroblasts, respectively, Kraft identified a common gene, GCH1, in the surviving cells by genetic sequencing [65]
