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Autophagy regulates lipid metabolism

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O'Roak, B

M2 macrophages are characterized by high expression of CD10, CD163, CD206, C-type lectin domain family 4 member L (CD209), and arginase 1 (Arg1) and release large amounts of the anti-inflammatory cytokines such as IL-10, TGF-, chemokine (C-C motif) ligand 1 (CCL1), chemokine (C-C motif) ligand 13 (CCL13), chemokine (C-C motif) ligand 14 (CCL14), chemokine (C-C motif) ligand 17 (CCL17), chemokine (C-C motif) ligand 18 (CCL18), chemokine (C-C motif) ligand 22 (CCL22), and chemokine (C-C motif) ligand 24 (CCL24) to exert effects in inflammation resolution, parasite clearance, immunomodulation, angiogenesis, tumor development, and tissue repair (4951)