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What are the benefits of inositol
Lysine can be monomethylated (Kme1), dimethylated (Kme2) and trimethylated (Kme3), and these modifications are reversible, and marks can be erased by lysine demethylases (PKDMs)
More importantly, SIRT3 can directly bind to SOD2, resulting in the deacetylation of SOD2 and enhancing the activity of SOD2, which plays an important role in regulating the homeostasis of ROS in mitochondria (Giralt and Villarroya, 2012)
Odermatt DC, Gari K (2017) The CIA targeting complex is highly regulated and provides two distinct binding sites for client ironsulfur proteins
