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In-depth quantitative multiplex proteomics reveal subtype-specific differences among functionally validated AML stem cell populations
The biochemical pathway involved with the metabolism of methionine to form S-Adenosylmethionine, homocysteine and the continuation of the cycle to form other biochemicals plays a central role in the metabolism of all mammalian cells
& Beutler, E
In humans, upon detecting oxidative stress, the NRF2 partner KEAP1 no longer ubiquitin-labels NRF2 for degradation, resulting in NRF2 stabilization and activation of NRF2-response genes
