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Discuss medication changes with healthcare providers

In OA, iron overload has been shown to alter the expression of iron metabolism-related proteins

Various studies have validated the anti-inflammatory and anti-fibrotic potential of alkaloids (Liu et al., 2023), polysaccharides, flavonoids, peptides, terpenoids, and polyphenols (Midgley et al., 2020), influencing the synthesis and secretion of pro-fibrotic factors (Li et al., 2017a), and regulating ECM synthesis and degradation, thereby offering therapeutic benefits for an anti-fibrotic treatment

Vina et al., 1989
