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Clinical observations report that patients using BPC-157 experience significant improvements in mobility and pain reduction, with some noting relief lasting six months or longer

The TGA codon, encoding Sec, is found in the first exon of the human GPx-1 gene at amino acid 48 (of about 203 total), and it is located 105 nucleotides from the splice junction, suggesting that the GPx-1 gene transcript may be susceptible to nonsense-mediated decay