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doi:10.1006/bbrc.2000.2800
STAT3 phosphorylation in hypothalamus of DIO mice STAT3 is specifically activated by leptin in vivo and in vitro

[DOI] [PubMed] [Google Scholar] [86].Liu PC, Chen YW, Centeno JA, Quezado M, Lem K, Kaler SG (2005)

Since night shift work is associated with the hypermethylation of genes involved in the circadian biorhythm [180], which is also involved in changes in melatonin secretion [112], it is plausible that melatonin may also directly change DNA methylation
