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In other studies, lower prevalence was found: 0% in morbidly obese Belgian children and adults (444), 1.9% in obese German children and adolescents (359,432), 1.8% in obese Finnish children (360), 1.7% in obese European Caucasians (430), 4.6% in Pima Indians (417), and 2.3% in North American severely obese adults (445)

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Accumulating evidence support a strong link between elevated circulating TMAO levels and fibrosis in the heart, kidney, liver, and skin in diverse diseases

A 2-year study of 100 patients with vitiligo, who were treated with oral folic acid (5 mg) and VitB12 (1 mg) in combination with sunlight exposure and UVB radiation, showed re-pigmentation in 52 participants with stable and progressive vitiligo