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As NAD+ decreases, mitochondrial oxidative phosphorylation suffers, which produces less ATP and more reactive oxygen species (ROS)
Clinical trials in patients with chronic wounds and diabetic ulcers have shown meaningful reductions in healing time

Clinical research has suggested that the levels of FOXO proteins in the central nervous system may be altered in research models of neurodegenerative disorders (NDDs)

Demonstrated functional improvements in Barth syndrome patients (increased muscle strength, improved exercise capacity) [3][10]
