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The cells were incubated with PBS, PBS + Laser, 28.8 g/mL PDA, 40 g/mL PDA@Pt (which contains 28.8 g/mL PDA), and 40 g/mL PDA@Pt + Laser (which contains 28.8 g/mL PDA, 1 W/cm 2 , 5 min) for 24 h

Schematic of Shimadzu's ion optical system (e.g

3.3 Lipid metabolism reprogramming: immune homeostasis disruption DM sustains systemic chronic inflammation through lipid-mediated pathways, in which prostaglandins (PGs), particularly the abundant PGE2, serve as both dual mediators and amplifiers of inflammatory cascades

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