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doi: 10.1126/science.289.5484.1550

Because peptides can target specific tissues or pathways, they offer a more precise approach than broad treatments like steroids or NSAIDs

Reduces joint pain and inflammation

Initial efforts involved synthesizing AngIV analogs with extended half-lives by incorporating reduced peptide bonds between residues, as exemplified by Divalinal-AngIV and Norleural-AngIV