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It also causes variety of toxicity including autophay, apoptosis, neurotoxicity, reproductive toxicity, tissue and organ toxicity and carcinogenicity in other organisms

2001;280:C621627
Diabetes Care 29:23652370 Zoratti M, Szabo I (1995) The mitochondrial permeability transition

Looking forward, GABA may have unique and previously underappreciated therapeutic benefits in TID to increase -cell content, reduce excess glucagon and curtail the inflammatory T-cell dysfunction of type 1 diabetes