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Description
Clinical impression in descending order was pigmented macules (n = 15, 45%), melanosis (n = 4, 12%), nevus (n = 3, 9%), melanoma (n = 2, 6%), melanoacanthoma (n = 1, 3%), and racial pigmentation (n = 1, 3%)
By damaging IL-17 cytokines, AIRE gene mutations are thought to impair the IL-17 pathway's function, resulting in CMC in people with APECED

AK1 (Lindstedt et al

If your real goal is fewer dark spots, less redness, or a smoother tone, you may get more from skin services that target those concerns without forcing melanin
