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Establishment of a novel autoimmune experimental model of bladder pain syndrome/interstitial cystitis in C57BL/6 mice

It should be pointed out that Griffith [11] originally validated this method in plasma where the artifactual oxidation of GSH is minimal, i.e., tolerable, because the GSH/GSSG ratio in plasma is much lower than in cells (~2 instead of ~400) [3], but this procedure has later been applied broadly to whole blood, red cells or other tissues in which GSH massively exceeds GSSG without proper modification

For over thirty years, Darren FX Clair, MD has helped thousands of people improve and maintain their overall health and vitality

Naiel et al., 2023)