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Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

Gastrointestinal issues are frequently the adverse effect of metformin medication that is most commonly observed, affecting 2-63% of T2DM patients, including diarrhea, nausea, vomiting, pain in the abdomen, and flatulence [47]

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