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Argyriou AA, Cavaletti G, Antonacopoulou A, Genazzani AA, Briani C, Bruna J, et al

(serving on the board of directors), Stelexis Biosciences Inc., Anvia Therapeutics Inc

In contrast, IRP2 knockdown or treatment with the ferroptosis inhibitor Fer-1 alleviates PC-12 cell damage by downregulating p53 levels and activating the SLC7A11-ALOX12 signaling pathway ( In summary, CDC42, derived from neural stem cell-derived exosomes, as well as TIGAR, FTO, and IRP2, contribute to PD pathology by regulating iron homeostasis, ferroptosis, fatty acid metabolism, the antioxidant system, and angiogenesis

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