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Activated microglia increase expression of proinflammatory cytokines including IL-1, IL-6, TNF-, and Ccl2, which stimulate microglial proliferation 53,54,55,56,57

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60 In another study, SCFA (butyrate and propionate, 5% by weight) consumption lowered hepatic fatty acid synthase activity and hepatic fat and increased the level of hepatic lipid oxidation in high-fat (45%) fed mice

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