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Annu Rev Pharmacol Toxicol 51:145167 Waxman D, Chang T (2015) Hormonal regulation of liver cytochrome p450 enzymes
Glucose is first converted to pyruvate in the cytoplasm, which is the first reaction of the aerobic oxidation pathway and also called glycolysis
However, functional effects of many polymorphisms remain unclear, and their influence can be gene- and cell type-specific, highlighting the complexity of genetic contributions to neurocognition (143)
In clinical settings, dosing schedules may be adjusted based on symptom improvement and feedback from regular medical evaluations
