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As the ATP synthesis rate does not meet demand, lower energy phosphate compounds such as AMP accumulate and are deaminated by AMPD3 into IMP and hypoxanthine, a phenomenon exponentially activated after storage week 3 [94]

The quantity of gas produced in the gut correlates positively with the severity of IBS symptoms, indicating that modulating gas production or promoting gas expulsion may help alleviate IBS symptoms

However, in the case of SIBO, the symptoms are often centered in the gut but may have systemic effects

Although a Th2-polarized response protects against this specific pathology, this does not necessarily imply that Th2 cells are responsible for protection after immunization