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Clinical trials using oral glucose tolerance testing demonstrated that AOD-9604 has no negative impact on carbohydrate metabolism or insulin sensitivity
Moreover, the altered gut environment in IBD, characterized by dysbiosis and bacterial overgrowth, may further exacerbate vitamin B12 deficiency, as some bacterial species can compete for or deplete cobalamin in the gastrointestinal tract
Human B12-dependent enzymes: Methionine synthase and Methylmalonyl-CoA mutase
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