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Subsequently, many other data were accumulated for a variety of biological systems [260,261,262], including human tissue models [263] and human tissue irradiated in vivo, where, however, a considerable individual variability in radiation response was observed [264]

The World Health organisation (WHO) estimates that approximately 552 million adults are expected to have diabetes by 2030, and diabetes-related cognitive dysfunction is likely to be a major challenge in terms of future health resource requirements (3, 4) (Figure 1)

Another study in adult rats showed that peripheral infusion of IGF-1 increased progenitor cell proliferation and selectively induced hippocampal neurogenesis [27]

Frank Loesser (1910-1969)