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Likewise, remarkable safety (i.e., LD50 higher than 2000 mg/kg through oral or intravenous route in mice) confirmed no adverse effect in toxicology studies (none of the animals died)
In an experimental setup designed by Volchegorskii et al., the effect of the drug in the alleviation of immobility was examined
Importantly, NBDHEX is also able to dissociate GSTP1-1 from its complexes with both JNK and TRAF2, thus enabling their activation 99
A deeper understanding of the role of CD44 in CSC biology and ferroptosis resistance is essential to develop innovative strategies to combat treatment-resistant cancers
