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Paeonol Ameliorates Imiquimod-Induced Psoriasis-like Skin Lesions in BALB/c Mice by Inhibiting the Maturation and Activation of Dendritic Cells

This study identified a small molecule that can disrupt KRAS4B association with a protein chaperone, altering KRAS4B membrane trafficking and cellular activity

As discussed in earlier sections, while epigenetic drugs have considerable theoretical potential for reprogramming cancer cell fate, their objective response rates as monotherapies in solid tumors have generally been modest [18]

Notably, L-cysteine emerged as the most effective inhibitor, followed by mercaptoethanol, ascorbic acid, and glutathione (Fig