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This concentration-dependent phenomenon is referred to as the MSE, being highly significant in MALDI-MS
For instance, the interaction of MPO with neutrophil CD11b/CD18 integrins enhances tyrosine phosphorylation, leading to the activation of protein tyrosine kinases that are involved in the regulation of degranulation and neutrophil respiratory burst [314]
In addition to being directly related to pathogenesis, 27-OHC is also closely associated with AD-associated events
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