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Wang and colleagues modeled IIAMD in mice by pre-fasting mice and then injecting them with LPS to confirm in vitro findings in vivo
Ferroptosis has been identified as an iron dependent non-apoptotic mechanism of cell death, mediated by accumulation of lipid peroxides that cause a rapid and unrepairable damage of the plasma membrane 10
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The prescribing provider sets the dose and adjusts based on clinical response throughout the cycle
